Further observations on the metaplasia of an amoeba, Naegleria gruberi.

Some Observations on the Actions of Steroids on the Metaplasia of the Amoeba, Naegleria Gruberi.

Cytopathogenicity of Naegleria gruberi for rat neuroblastoma cell cultures.

Amoebae of Naegleria gruberi were cytopathic for cultures of rat neuroblastoma (B-103) cells. N. gruberi grew and destroyed B-103 cells at 30 degrees C. As few as one amoeba inoculated per million B-103 cells resulted in cytopathogenicity after extensive growth of N. gruberi.

A Nonmitochondrial Hydrogen Production in Naegleria gruberi

Naegleria gruberi is a free-living heterotrophic aerobic amoeba well known for its ability to transform from an amoeba to a flagellate form. The genome of N. gruberi has been recently published, and in silico predictions demonstrated that Naegleria has the capacity for both aerobic respiration and anaerobic biochemistry to produce molecular hydrogen in its mitochondria. This finding was conside...

Expression of the nfa1 gene cloned from pathogenic Naegleria fowleri in nonpathogenic N. gruberi enhances cytotoxicity against CHO target cells in vitro.

The pathogenic amoeba Naegleria fowleri has a 360-bp nfa1 gene that encodes the Nfa1 protein (13.1 kDa), which is located in the pseudopodia of the amoeba, and an anti-Nfa1 antibody reduces N. fowleri-induced mammalian-cell cytotoxicity in vitro. In contrast, an anti-Nfa1 antibody cannot detect Nfa1 protein expression in the nonpathogenic amoeba Naegleria gruberi, which also possesses the nfa1 ...

An experimental study of the interaction between the soil amoeba Naegleria gruberi and a glass substrate during amoeboid locomotion.

The amoeboid locomotion of the soil protozoon Naegleria gruberi has been studied using reflexion-interference microscopy. Two types of contact are made with a planar glass substrate. One, formed at a considerable distance from the substrate in deionized water (congruent to 100 nm) has been termed 'associated contact' and usually involves a considerable surface area (of the order of 100 micromet...